• First choice is metformin. If GI disturbance, metformin MR.
  • Lifestyle management including diet, weight management and physical exercise should be an ongoing consideration at all stages.
  • If required short-term, rescue therapy for symptomatic hyperglycaemia - sulphonylurea, insulin.

Is there existing ASCVD, HF, CKD?

Second line therapy aims: improvement in cardiorenal outcomes, achievement of target

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