• Nebulised saline can be considered for sputum clearance in bronchiectasis if airways clearance techniques are not effective.
  • Available concentrations are 0.9% (“Normal” saline), and 3%, 6%, 7% (hypertonic saline).
  • Perform an airway reactivity challenge test when inhaled mucoactive treatment is first administered.62
  • There is currently no evidence to recommend any concentration of saline over any other, though side effects may limit the higher concentrations in use.
  • The dosing schedule is four ml of saline nebulised two to four times per day.