Warning

Annual vaccination is essential for all those ‘at risk’ of influenza.

GPs may only prescribe antiviral medicines for the prophylaxis and treatment of influenza under the General Medical Services (GMS) regulations when the Chief Medical Officer (CMO) has confirmed that influenza is circulating in the community.

Antivirals are not recommended for healthy adults. Treat ‘at risk’ patients when influenza is circulating in the community, or in a care home where influenza is likely. Ideally treat within 48 hours of onset (or within 36 hours for zanamivir treatment in children).

At risk: pregnant (including up to two weeks post-partum), children under 6 months, adults 65 years or older, chronic respiratory disease (including COPD and asthma), significant cardiovascular disease (not hypertension), severe immunosuppression, diabetes mellitus, chronic neurological, renal or liver disease, morbid obesity (BMI ≥ 40).

Drug details

Drug

First choice:

Oseltamivir

Dosage

75mg

Duration

twice daily for 5 days

child dose

Drug

Resistance to oseltamivir or severe immunosuppression:

Zanamivir

Dosage

10mg

Duration

twice daily (2 inhalations by diskhaler for up to 10 days).

child dose

See Public Health England Influenza guidance for treatment of patients under 13 years or in severe immunosuppression.

Editorial Information

Last reviewed: 18/05/2022

Next review date: 18/05/2025

Author(s): NHS Lanarkshire Antimicrobial Management Committee, Dr Dundas, Dr Hylands, S McCormick, Heather Boyle.

Version: V1

Approved By: AMC; ADTC

Reviewer name(s): NHS Lanarkshire Antimicrobial Management Committee.

Document Id: June 2022