Warning

Aim to choose the lowest dosage of oestrogen and progestogen that:

  • maintains efficacy
  • has fewest side effects
  • gives good cycle control
  • takes into account differential risk of VTE
  • is cost effective.

A monophasic COC containing 20 to 35 micrograms of ethinylestradiol with a low dose of either norethisterone or levonorgestrel is a suitable first line option. Examples are Rigevidon, Ovranette, Microgynon 30, Ovysmen and Brevinor. Tailored regimes may improve bleeding patterns and hence improve compliance. Please see FSRH guidance for alternative COC regimes. Transdermal or intravaginal preparations may be advantageous in situations where GI absorption is compromised, e.g. Inflammatory bowel disease, or in situations where this method will improve compliance.

 

CHC preparations

Monophasic preparations
Grouped by progestogen
type and generation
Oestrogen dose Brand names
Norethisterone (1st) 35 micrograms EE Brevinor
Norimin
Levonorgestrel (2nd) 30mcg EE Microgynon 30
Ovranette
Rigevidon
Levest
Maexeni
Ambelina
Desogestrel (3rd) 30mcg EE Marvelon
Gedarel 30/150
Cimizt
Desogestrel (3rd) 20mcg EE Mercilon
Gedarel 20/150
Bimizza
Gestodene (3rd) 30mcg EE Femodene®
Katya®
Akizza®
Millinette 30/75®
Gestodene (3rd) 20mcg EE Femodette
Sunya
Millinette 20/75
Cyproterone
(equivalent to 3rd)
35mcg EE Co-cyprindiol
Dianette®
Clairette®
Teragezza®
Norgestimate (3rd) 35mcg EE Cilique
Lizinna
Drospirenone (4th) 20mcg EE

Eloine
Drospirenone (4th) 30mcg EE Yasmin®
Lucette
Yacella
Dretine
Yiznell
Dretine
Triphasic pills with
varied progestogens
30 to 40mcg EE TriRegol
Triadene
Phasic with Dienogest (4th) 1 to 3mg estradiol
valerate
Qlaira
Nomegestrel acetate (4th) 1.5mg estradiol
hemihydrate
Zoely
Low dose patch
with norelgestromin
20mcg EE Evra
Intravaginal ring
with etonogestrel
15mcg EE Nuvaring

Prices vary between health boards and between Primary and Secondary Care. First
choice preparation will be guided by the stock arrangements/availability within each
service.

Editorial Information

Last reviewed: 31/05/2022

Next review date: 31/05/2024

Author(s): West of Scotland Managed Clinical Network for Sexual Health Clinical Guidelines Group.

Version: 7.1

Approved By: West of Scotland Managed Clinical Network for Sexual Health